CVE-2025-10937

Oxford Nanopore Technologies MinKNOW Improper Check for Unusual or Exceptional Conditions

Published Oct 23, 2025 CVSS 4.0 · 6.8 Medium EPSS < 1% KEV · Not listed
Description
Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 creates a temporary file to store the local authentication token during startup, before copying it to its final location. This temporary file is created in a directory accessible to all users on the system. An unauthorized local user or process can exploit this behavior by placing a file lock on the temporary token file using the flock system call. This prevents MinKNOW from completing the token generation process. As a result, no valid local token is created, and the software is unable to execute commands on the sequencer. This leads to a denial-of-service (DoS) condition, blocking sequencing operations.

Remediation

Vendor Solution

Oxford Nanopore Technologies recommends users upgrade to MinKNOW Versions later than 24.11 https://nanoporetech.com/software/  to eliminate these vulnerabilities. If users are unable to upgrade to v24.11 to reduce risk from the remaining Authentication Token and Token Lock vulnerabilities, Oxford Nanopore advises the following additional measures for users on version 24.06: * Remote Connect: Keep Remote Connect disabled in MinKNOW unless strictly required, and enable it only within trusted network environments. * Endpoint Protection: Install and maintain antivirus and malware scanning tools to mitigate denial-of-service (DoS) conditions arising from local exploitation or malware. Users running older versions of MinKNOW who cannot upgrade immediately should contact Oxford Nanopore Support https://nanoporetech.com/about/contact  for guidance on securing their configurations. Downloading the release requires users to be logged into the Nanopore Community.

Tracking

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Advisories

No advisories available
History
Type Values Removed Values Added
First Time appeared Nanoporetech
Nanoporetech minknow
Vendors & Products Nanoporetech
Nanoporetech minknow
Type Values Removed Values Added
Metrics ssvc

{'options': {'Automatable': 'no', 'Exploitation': 'none', 'Technical Impact': 'partial'}, 'version': '2.0.3'}

Type Values Removed Values Added
Description Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 creates a temporary file to store the local authentication token during startup, before copying it to its final location. This temporary file is created in a directory accessible to all users on the system. An unauthorized local user or process can exploit this behavior by placing a file lock on the temporary token file using the flock system call. This prevents MinKNOW from completing the token generation process. As a result, no valid local token is created, and the software is unable to execute commands on the sequencer. This leads to a denial-of-service (DoS) condition, blocking sequencing operations.
Title Oxford Nanopore Technologies MinKNOW Improper Check for Unusual or Exceptional Conditions
Weaknesses CWE-754
References
Metrics cvssV3_1

{'score': 5.5, 'vector': 'CVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:N/I:N/A:H'}

cvssV4_0

{'score': 6.8, 'vector': 'CVSS:4.0/AV:L/AC:L/AT:N/PR:L/UI:N/VC:N/VI:N/VA:H/SC:N/SI:N/SA:N'}

Weaknesses

Sources

Status
PUBLISHED
Assigner
icscert
Published
Updated
Oct 23, 2025, 7:11 PM
Reserved
Sep 24, 2025, 10:17 PM
Status
Deferred
Published
Oct 23, 2025, 7:15 PM
Modified
Oct 8, 2026, 11:10 AM